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What is the new sweetener hesperidin

February 09, 2023
What Is Hesperetin?

Naringenin  in 7 carbon position and new hesperidose into glycosides, called naringenin, taste extremely bitter. It is a sweetener with a sweetness up to 2 000 times that of sucrose when the ring is opened and hydrogenated to form dihydrochalcone compounds under alkaline conditions. Hesperidin exists in large quantities in citrus peel.

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Hesperidin forms glycosides with rutin at 7 carbon position, which is called neohesperidin, and β-neohesperidin forms glycosides at 7 carbon position.

Functions and Benefits of Hesperetin?
Hesperidin has the effects of strengthening the stomach, expectorating phlegm, relieving cough, dispelling wind, diuresis, antiviral, antibacterial, anti-reflux and anti-stomachache.

Aplication
(1) Antioxidant effect: Hesperidin can avoid the harm caused by peroxide reaction by removing peroxynitrite ions. 
(2) Anti-inflammatory effect: hesperidin can inhibit the mediating effect of inflammatory mediators, thereby indirectly inhibiting inflammatory response. Hesperidin has a stronger anti-inflammatory effect than hesperidin, and hesperidin C7 has an effect on its anti-inflammatory activity after binding to rutin.
 (3) hypolipidemic effect: hesperidin can inhibit the action of cholesterol generating enzyme and esterification enzyme, so as to achieve the effect of hypolipidemic.

 (4) Cardiovascular protection: hesperidin has the effect of reducing blood fat and vascular permeability, and can prevent thrombosis. Hesperidin can also protect endothelial cells from hypoxia by stimulating certain mitochondrial enzymes such as succinate dehydrogenase and prevent thrombus formation induced by clotting caused by endothelial cell necrosis. In addition, hesperidin promotes antiplatelet clotting activity by inhibiting the phosphorylation of PLCγ2 and its downstream signaling, which can prevent the formation of thrombus and is beneficial to the cardiovascular system. (5) Anti-tumor effect: hesperidin has antioxidant effect, which can avoid the cancer caused by genetic changes caused by these factors. Promote the flow of P-glycoprotein-mediated drugs from tumor cells, and flavonoids (hesperidin, etc.) can change the blood-brain barrier permeability to vincristine, which is also related to its concentration. Low concentration of flavonoids can reduce the uptake of vincristine by brain capillary endothelial cells. On the contrary, high concentration has a promoting effect.


Shaanxi Huike Botanical Development Co., Ltd. a integrated enterprise which is focus on natural products, plant extract related products and services.We mainly focus on pharmaceutical, functional food, Freeze-dried powder,Natural Pigment,beverages and other business services.

Shaanxi Huike Botanical Development Co., Ltd. a integrated enterprise which is focus on natural products, plant extract related products and services.We mainly focus on pharmaceutical, functional food, Freeze-dried powder,Natural Pigment,Homology of medicine and food,beverages and other business services.
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